The Regent Palace Hotel is located in Glasshouse Street, London and was by John Mowlem. At that time, it was the largest hotel in Europe with 1028 bedrooms. The hotel is situated opposite the statue of Eros, in Piccadilly Circus, near Shaftesbury Avenue, Leicester Square and Regent Street. The Regent Palace Hotel was located on a triangular site close to the north side of Piccadilly Circus bordered by Glasshouse Street, Sherwood Street, Brewer Street and Air Street. The hotel was completed in 1915.

The building is a steel-framed structure and required 6000 tons of steelwork for the structure. There are nine floors above ground level. In its early days it was owned and managed by J. Lyons and Co who formed a subsidiary company called Strand Hotels Limited. During the First World War, a considerable section of the hotel was requisitioned by the British Government and during the Second World War, 2 separate bombs caused minor damage to the hotel

Located near Soho, it was an obvious meeting point for ladies of the night to ply their trade in the 1960’s. These days have long gone through legislation and Soho has retreated back to its old boundaries. The Regent Palace closed on the 31st of December 2006 the hotel became increasingly uneconomic to operate as a hotel to the standards required by a 21st century clientele. The Crown Estate plans to redevelop it. The historic art-deco Atlantic Bar and Grill and Titanic Restaurant will be preserved.